Crossword clues for Most ineffective. 6 lettersAnswerClueOTIOSEIneffectiveNEGATEMake ineffectiveNEGATERender ineffectiveOFFDAYIneffective periodFUTILECompletely ineffectiveDOTARDOld, ineffective sortNEUTERRender ineffectiveFEEBLEIneffectiveFUTILEIneffectiveOFFDAYUnusually ineffective 24 hoursTONICSIneffective concoctionsOFFDAYPeriod of relative ineffectivenessLAMESTMost ineffective.INEFFECTActually.INEFFECTVirtually.INEFFECTIVEUselessINEFFECTFor practical purposesINEFFECTEssentiallyEMPTYSUITIneffective executive, metaphoricallyTOOTHLESSIneffectivePOINTLESSIneffectiveGETTINGTHEHOOKIneffective pitcher's fate, in baseball lingo [Villain 2]VOIDIneffectiveNOICECut __ (be ineffective)FAULTYSEISMOLOGISTIneffective earth scientist?AVAILTo no __ (ineffective)DUDIneffective ammoNEUTRALIZEDMade ineffectiveWEARSOFFBecomes ineffectiveABLEAntonym of "ineffective"USELESSIneffectiveSADSACKIneffective soldier: Slang.DUDIneffective person: Slang.STERILEIneffective.NULLSMakes ineffective.IDLEIneffective.LAMEIneffective.SADSACKSWell-meaning but ineffective people: Slang.WISHFULTHINKINGPleasant but ineffective mental exercise.VITIATERender ineffective.HAMSTRUNGMade ineffective.NEUTRALIZEMake ineffective.PUTTEREDBusied (oneself) ineffectively.ANNULMake ineffective.IDLYIneffectively.PARALYZINGMaking ineffective.DRAWSTHETEETHOFRenders ineffectiveWANIneffectiveSPIKESTHEGUNSRenders ineffectivePUTSOUTOFGEARRenders ineffective