Crossword clues for It's a downer 6 lettersAnswerClueDOWNERBarbiturateDOWNERDepressing situationDOWNERSuccessful tackler.DOWNERBuzzkillDOWNERBit of melancholiaDOWNERAddict's pillDOWNERDepressantDOWNERIt'll bum you outDOWNERDispiriting experienceDOWNERAny depressing thingDOWNERKilljoyDOWNERDepressing experienceDOWNERReal dragDOWNERBad mood inducerDOWNERBad sceneDOWNERDepressing state of affairsDOWNERWet blanketDOWNERBad experienceDOWNERSedative, informallyDOWNERSomething depressingDOWNERTackler.DOWNERDragOPIATEIt's a real downerTRANKSDowners, slangilyHOWSADThat's a downerDAMPERIt's put on by Debbie DownersDEBBIE___ Downer (pessimistic person)VETOERBill turner-downerJETLAGTravel downerOPIATEIt can be a real downerTRANKSDowners, in briefOPIATEDrug that's a downerOPIATEDownerOPIATEIt's a downerSHOWERPicnic downerHUMANS43-Downers?RAINERA shower-downer.NOSALERep's downerDRATCHRachel who portrayed Debbie Downer on "S.N.L."DOWNERSBarbsDOWNERSThey're a dragDOWNERSDepressantsDOWNERSBad scenesDOWNERSSun ___, hobos of Australia.DOWNERSMood killersDOWNERSDepressing experiencesDOWNERSDragsDOWNERSDepressing doingsDOWNERSClever tacklers.ANTISThumbs-downers